Effect of Human Serum on Biofilm Formation by Oral Mycoplasma on Nitinol Surfaces

The formation of a biofilm is considered a strategy of bacteria to ensure their survival, for once they are embedded in this structure they are difficult to eradicate and are protected from antimicrobials and immune responses from the host. More than 80% of microbial infections in humans, including dental caries and gingival-periodontal diseases, are caused by bacteria organized in biofilms [1,2]. Dental plaque harbors a wide variety of microorganisms. There are studies reported in the literature demonstrating the presence of Mycoplasma in subgingival plaque associated with periodontal disease [3-5].